Molecular Diagnostic Probe Free Sample

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Jan 7, 2019
CCND1(BCL1) gene amplification probe
◆Product Advantages
1.Fleetness: Tissue probe hybridization time: 2 hours. Cell probe hybridization time: 1 hour.
2.Accuracy: Less non-specific background staining (dyeing). Increase difficult samples detection rate.
3.Reproducibility: Different laboratories test results are highly reproducible.

◆Probe Description
The CCND1 gene amplification probe uses orange-red dye to mark CCND1(BCL1) region, and the green dye to mark the centromeric region of chromosome 11 (CEP 11 ). The CCND1 gene marker region is located in 11q13.3, and the CEP11 probe is labeled with a specific alpha satellite sequence.

◆Clinical Significance
CCND1 gene amplification indicates that CCND1 gene plays an important role in tumor development. Patients with CCND1 gene amplification have poor prognosis and are closely related to chemotherapy resistance.

◆Size Specifications

Motokura T, et al. (1991) Nature 350: 512-5.
Ormandy CJ, et al. (2003) Breast Cancer Res Treat 78: 323-35.Molecular Diagnostic Probe Free Sample
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